Now showing items 1-6 of 6

    • Herrada, Andrés A.; Contreras, Francisco J.; Marini, Natacha P.; Amador, Cristian A.; González, Pablo A.; Cortés, Claudia M.; Riedel, Claudia A.; Carvajal, Cristián A.; Figueroa, Fernando; Michea Acevedo, Luis; Fardella, Carlos E.; Kalergis, Alexis M. (American Association of Immunologists, 2010)
      Excessive production of aldosterone leads to the development of hypertension and cardiovascular disease by generating an inflammatory state that can be promoted by T cell immunity. Because nature and intensity of T cell ...
    • González, Liliana A.; Melo González, Felipe; Sebastián, Valentina P.; Vallejos, Omar P.; Noguera, Loreani P.; Suazo, Isidora D.; Schultz Lombardic, Barbara Melinka; Manosalva, Andrés H.; Peñaloza, Hernán F.; Soto, Jorge A.; Parker, Dane; Riedel, Claudia A.; González, Pablo A.; Kalergis, Alexis M.; Bueno, Susan M. (Frontiers Media, 2021)
      Neutrophils are immune cells classically defined as pro-inflammatory effector cells. However, current accumulated evidence indicates that neutrophils have more versatile immune-modulating properties. During acute lung ...
    • Arriagada, Alejandro A.; Albornoz, Eduardo; Opazo, María Cecilia; Becerra, Álvaro; Vidal, Gonzalo; Fardella, Carlos; Michea Acevedo, Luis; Carrasco, Nancy; Simón, Felipe; Elorza, Álvaro A.; Bueno, Susan M.; Kalergis, Alexis M.; Riedel, Claudia A. (Endocrine Society, 2015)
      Na+/I- symporter (NIS) mediates iodide (I-) uptake in the thyroid gland, the first and rate-limiting step in the biosynthesis of the thyroid hormones. The expression and function of NIS in thyroid cells is mainly regulated ...
    • Opazo, María Cecilia; Fuentes Pena, Camilo; Méndez, Luis; Rojas, Diana; Aguayo, Daniel; Oyanedel, Juan Carlos; Moreno Reyes, Rodrigo; Wohllk González, Nelson Jorge; Kalergis, Alexis M.; Riedel, Claudia A. (Springer, 2023)
      Adequate iodine nutrition is fundamental for all humans and is critical during pregnancy and lactation due to iodine forms part of the structure of thyroid hormones (THs) and it is required for THs function. Iodine is a ...
    • Opazo, M. C.; Gianini, A.; Pancetti, F.; Azkcona, G.; Alarcón, L.; Lizana, R.; Noches, V.; Gonzalez, P. A.; Porto, M.; Mora Gutiérrez, Sergio; Rosenthal, D.; Eugenin, E.; Naranjo, D.; Kalergis, Alexis M.; Riedel, Claudia A. (Endocrine Society, 2008-10)
      Neurological deficits in the offspring caused by human maternal hypothyroxinemia are thought to be irreversible. To understand the mechanism responsible for these neurological alterations, we induced maternal hypothyroxinemia ...
    • Mackern-Oberti, Juan Pablo; Llanos, Carolina; Vega, Fabián; Salazar Onfray, Flavio; Riedel, Claudia A.; Bueno, Susan M.; Kalergis, Alexis M. (Elsevier, 2015)
      Dendritic cells (DCs) play a key role in the activation of the immune response against pathogens, as well as in the modulation of peripheral tolerance to self-antigens (Ags). Furthermore, an imbalance in the activating/inhibitory ...